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BMCBI
2008
124views more  BMCBI 2008»
15 years 6 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2008
154views more  BMCBI 2008»
15 years 6 months ago
Extension of the COG and arCOG databases by amino acid and nucleotide sequences
Background: The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequen...
Florian Meereis, Michael Kaufmann
BMCBI
2008
100views more  BMCBI 2008»
15 years 6 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Effects of dependence in high-dimensional multiple testing problems
Background: We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR) contro...
Kyung In Kim, Mark A. van de Wiel
BMCBI
2008
139views more  BMCBI 2008»
15 years 6 months ago
Hierarchical structure of cascade of primary and secondary periodicities in Fourier power spectrum of alphoid higher order repea
Background: Identification of approximate tandem repeats is an important task of broad significance and still remains a challenging problem of computational genomics. Often there ...
Vladimir Paar, Nenad Pavin, Ivan Basar, Marija Ros...
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