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BMCBI
2007
122views more  BMCBI 2007»
15 years 6 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
ICCV
2007
IEEE
16 years 8 months ago
Spherical-Homoscedastic Shapes
Shape analysis requires invariance under translation, scale and rotation. Translation and scale invariance can be realized by normalizing shape vectors with respect to their mean ...
Onur C. Hamsici, Aleix M. Martínez
CORR
2010
Springer
127views Education» more  CORR 2010»
15 years 6 months ago
Statistical and Computational Tradeoffs in Stochastic Composite Likelihood
Maximum likelihood estimators are often of limited practical use due to the intensive computation they require. We propose a family of alternative estimators that maximize a stoch...
Joshua Dillon, Guy Lebanon
RECOMB
2002
Springer
16 years 7 months ago
A Survey of Computational Methods for Determining Haplotypes
It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (...
Bjarni V. Halldórsson, Vineet Bafna, Nathan...