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BMCBI
2010
126views more  BMCBI 2010»
15 years 6 months ago
A boosting method for maximizing the partial area under the ROC curve
Background: The receiver operating characteristic (ROC) curve is a fundamental tool to assess the discriminant performance for not only a single marker but also a score function c...
Osamu Komori, Shinto Eguchi
BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2010
92views more  BMCBI 2010»
15 years 6 months ago
HORI: a web server to compute Higher Order Residue Interactions in protein structures
Background: Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like...
Pandurangan Sundaramurthy, Khader Shameer, Raashi ...
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
BMCBI
2010
134views more  BMCBI 2010»
15 years 6 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
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