23098 search results - page 4224 / 4620 » Component Based Development |
191
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BMCBI
2006
15 years 6 months ago
2006
Background: Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly availa...
223
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BMCBI
2006
15 years 6 months ago
2006
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
219
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BMCBI
2006
15 years 6 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
168
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BMCBI
2006
15 years 6 months ago
2006
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
224
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BMCBI
2006
15 years 6 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...