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AC
1998
Springer
15 years 6 months ago
Cellular Automata Models of Self-Replicating Systems
Abstract: Since von Neumann's seminal work around 1950, computer scientists and others have studied the algorithms needed to support self-replicating systems. Much of this wor...
James A. Reggia, Hui-Hsien Chou, Jason D. Lohn
BMCBI
2011
15 years 1 months ago
Hierarchical graphs for rule-based modeling of biochemical systems
Background: In rule-based modeling, graphs are used to represent molecules: a colored vertex represents a component of a molecule, a vertex attribute represents the internal state...
Nathan W. Lemons, Bin Hu, William S. Hlavacek
VLSID
1998
IEEE
116views VLSI» more  VLSID 1998»
15 years 11 months ago
Synthesis of Testable RTL Designs
With several commercial tools becoming available, the high-level synthesis of applicationspeci c integrated circuits is nding wide spread acceptance in VLSI industry today. Existi...
C. P. Ravikumar, Sumit Gupta, Akshay Jajoo
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
AAAI
1994
15 years 8 months ago
Knowledge Refinement in a Reflective Architecture
A knowledge acquisition tool should provide a user with maximum guidance in extending and debugging a knowledge base, by preventing inconsistencies and knowledge gaps that may ari...
Yolanda Gil