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BMCBI
2008
155views more  BMCBI 2008»
15 years 6 months ago
AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
Tania Pencheva, David Lagorce, Ilza Pajeva, Bruno ...
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
177
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JAIR
2008
113views more  JAIR 2008»
15 years 6 months ago
Graphical Model Inference in Optimal Control of Stochastic Multi-Agent Systems
In this article we consider the issue of optimal control in collaborative multi-agent systems with stochastic dynamics. The agents have a joint task in which they have to reach a ...
Bart van den Broek, Wim Wiegerinck, Bert Kappen
NECO
2008
108views more  NECO 2008»
15 years 6 months ago
Optimization of Decision Making in Multilayer Networks: The Role of Locus Coeruleus
Previous theoretical work has shown that a single layer neural network can implement the optimal decision process for simple, two alternative forced choice (2AFC) tasks. However, ...
Eric Shea-Brown, Mark S. Gilzenrat, Jonathan D. Co...
ICDE
2005
IEEE
122views Database» more  ICDE 2005»
16 years 8 months ago
Uncovering Database Access Optimizations in the Middle Tier with TORPEDO
A popular architecture for enterprise applications is one of a stateless object-based server accessing persistent data through Object-Relational mapping software. The reported ben...
Bruce E. Martin