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BMCBI
2010
122views more  BMCBI 2010»
15 years 6 months ago
Simultaneous prediction of transcription factor binding sites in a group of prokaryotic genomes
Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
Shaoqiang Zhang, Shan Li, Phuc T. Pham, Zhengchang...
BMCBI
2010
102views more  BMCBI 2010»
15 years 6 months ago
Peptide binding predictions for HLA DR, DP and DQ molecules
Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
Peng Wang, John Sidney, Yohan Kim, Alessandro Sett...
BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Alinda Nagy, Hédi Hegyi, Krisztina Farkas, ...
BMCBI
2007
148views more  BMCBI 2007»
15 years 6 months ago
Toward the automated generation of genome-scale metabolic networks in the SEED
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
Matthew DeJongh, Kevin Formsma, Paul Boillot, John...
BMCBI
2008
128views more  BMCBI 2008»
15 years 6 months ago
HAPSIMU: a genetic simulation platform for population-based association studies
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
Feng Zhang, Jianfeng Liu, Jie Chen, Hong-Wen Deng