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» Clustering cancer gene expression data: a comparative study
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CANDC
2004
ACM
15 years 6 months ago
The difficult interpretation of transcriptome data: the case of the GATC regulatory network
Genomic analyses on part of Escherichia coli's chromosome had suggested the existence of a GATC regulated network. This has recently been confirmed through a transcriptome an...
Alessandra Riva, Marie-Odile Delorme, Tony Chevali...
BMCBI
2006
122views more  BMCBI 2006»
15 years 6 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2007
168views more  BMCBI 2007»
15 years 6 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
BMCBI
2007
160views more  BMCBI 2007»
15 years 6 months ago
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...
BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...