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» Clustering cancer gene expression data: a comparative study
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BMCBI
2002
89views more  BMCBI 2002»
15 years 6 months ago
Sources of variability and effect of experimental approach on expression profiling data interpretation
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
BMCBI
2007
140views more  BMCBI 2007»
15 years 6 months ago
Evaluation of high-throughput functional categorization of human disease genes
Background: Biological data that are well-organized by an ontology, such as Gene Ontology, enables high-throughput availability of the semantic web. It can also be used to facilit...
James L. Chen, Yang Liu, Lee T. Sam, Jianrong Li, ...
BMCBI
2008
201views more  BMCBI 2008»
15 years 6 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2011
15 years 20 days ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
CSB
2005
IEEE
202views Bioinformatics» more  CSB 2005»
15 years 11 months ago
Head and Neck Cancer Metastasis Prediction via Artificial Neural Networks
Cancers in head and neck tends to spread to nearby lymph nodes. Lymph nodes trap the spreading tumor cells but then the tumor starts to grow in these nodes and then spread further...
Eveleen Darby, Tezeswari Nettimi, Shilpa Kodali, L...