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BMCBI
2010
123views more  BMCBI 2010»
15 years 6 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
COLT
1997
Springer
15 years 10 months ago
Estimation of Time-Varying Parameters in Statistical Models: An Optimization Approach
Abstract. We propose a convex optimization approach to solving the nonparametric regression estimation problem when the underlying regression function is Lipschitz continuous. This...
Dimitris Bertsimas, David Gamarnik, John N. Tsitsi...
ICCV
2011
IEEE
14 years 6 months ago
Generalized Roof Duality for Pseudo-Boolean Optimization
The number of applications in computer vision that model higher-order interactions has exploded over the last few years. The standard technique for solving such problems is to red...
Fredrik Kahl, Petter Strandmark
ICDM
2006
IEEE
131views Data Mining» more  ICDM 2006»
16 years 13 days ago
Dimension Reduction for Supervised Ordering
Ordered lists of objects are widely used as representational forms. Such ordered objects include Web search results and best-seller lists. Techniques for processing such ordinal d...
Toshihiro Kamishima, Shotaro Akaho
ML
2012
ACM
385views Machine Learning» more  ML 2012»
14 years 2 months ago
An alternative view of variational Bayes and asymptotic approximations of free energy
Bayesian learning, widely used in many applied data-modeling problems, is often accomplished with approximation schemes because it requires intractable computation of the posterio...
Kazuho Watanabe