Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Drawing on the correspondence between the graph Laplacian, the Laplace-Beltrami operator on a manifold, and the connections to the heat equation, we propose a geometrically motiva...
— We propose a feature selection criterion based on kernel discriminant analysis (KDA) for an -class problem, which finds eigenvectors on which the projected class data are loca...
The cluster assumption is exploited by most semi-supervised learning (SSL) methods. However, if the unlabeled data is merely weakly related to the target classes, it becomes quest...
The biological sciences are undergoing an explosion in the amount of available data. New data analysis methods are needed to deal with the data. We present work using KDD to analys...