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BIOCOMP
2008
15 years 8 months ago
Discoveries in shRNA Design
-- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
Hong Zhou, Xiao Zeng, Joseph Manthey
IOPADS
1996
100views more  IOPADS 1996»
15 years 7 months ago
ENWRICH a Compute-Processor Write Caching Scheme for Parallel File Systems
Many parallel scientific applications need high-performance I/O. Unfortunately, end-to-end parallel-I/O performance has not been able to keep up with substantial improvements in p...
Apratim Purakayastha, Carla Schlatter Ellis, David...
MOBICOM
2010
ACM
15 years 6 months ago
Challenge: mobile optical networks through visual MIMO
Mobile optical communications has so far largely been limited to short ranges of about ten meters, since the highly directional nature of optical transmissions would require costl...
Ashwin Ashok, Marco Gruteser, Narayan Mandayam, Ja...
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...
BMCBI
2008
109views more  BMCBI 2008»
15 years 6 months ago
LTRharvest, an efficient and flexible software for de novo detection of LTR retrotransposons
Background: Transposable elements are abundant in eukaryotic genomes and it is believed that they have a significant impact on the evolution of gene and chromosome structure. Whil...
David Ellinghaus, Stefan Kurtz, Ute Willhoeft