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BMCBI
2006
117views more  BMCBI 2006»
15 years 6 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
CORR
2006
Springer
102views Education» more  CORR 2006»
15 years 6 months ago
Similarity of Objects and the Meaning of Words
We survey the emerging area of compression-based, parameter-free, similarity distance measures useful in data-mining, pattern recognition, learning and automatic semantics extracti...
Rudi Cilibrasi, Paul M. B. Vitányi
BMCBI
2005
141views more  BMCBI 2005»
15 years 6 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
BMCBI
2005
82views more  BMCBI 2005»
15 years 6 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
BMCBI
2005
124views more  BMCBI 2005»
15 years 6 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...