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BMCBI
2008
118views more  BMCBI 2008»
15 years 7 months ago
DOVIS: an implementation for high-throughput virtual screening using AutoDock
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
Shuxing Zhang, Kamal Kumar, Xiaohui Jiang, Anders ...
BMCBI
2006
113views more  BMCBI 2006»
15 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
GRID
2006
Springer
15 years 7 months ago
Toward an On-Demand Restricted Delegation Mechanism for Grids
Grids are intended to enable cross-organizational interactions which makes Grid security a challenging and nontrivial issue. In Grids, delegation is a key facility that can be used...
Mehran Ahsant, Jim Basney, Olle Mulmo, Adam J. Lee...
SIAMSC
2008
113views more  SIAMSC 2008»
15 years 7 months ago
An Efficient and Robust Method for Simulating Two-Phase Gel Dynamics
We develop a computational method for simulating models of gel dynamics where the gel is described by two phases, a networked polymer and a fluid solvent. The models consist of tra...
Grady B. Wright, Robert D. Guy, Aaron L. Fogelson
SP
2008
IEEE
122views Security Privacy» more  SP 2008»
15 years 7 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...