Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
pecific models increase the level of abstraction used to develop large-scale component-based systems. Model-driven development (MDD) approaches (e.g., ModelIntegrated Computing and...
Krishnakumar Balasubramanian, Aniruddha S. Gokhale...
Numerical modelling is now used routinely to make predictions about the behaviour of environmental systems. Model calibration remains a critical step in the modelling process and ...
Modern programs make extensive use of reusable software libraries. For example, a study of a number of large Java applications shows that between 17% and 30% of the classes in tho...
Johannes Henkel, Christoph Reichenbach, Amer Diwan