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BMCBI
2006
103views more  BMCBI 2006»
15 years 6 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
Improved Chou-Fasman method for protein secondary structure prediction
Background: Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique ha...
Hang Chen, Fei Gu, Zhengge Huang
BMCBI
2006
122views more  BMCBI 2006»
15 years 6 months ago
Genome comparison using Gene Ontology (GO) with statistical testing
Background: Automated comparison of complete sets of genes encoded in two genomes can provide insight on the genetic basis of differences in biological traits between species. Gen...
Zhaotao Cai, Xizeng Mao, Songgang Li, Liping Wei
BMCBI
2006
117views more  BMCBI 2006»
15 years 6 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
BMCBI
2006
127views more  BMCBI 2006»
15 years 6 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...