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BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
BMCBI
2007
175views more  BMCBI 2007»
15 years 6 months ago
Fast automated cell phenotype image classification
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
Nicholas A. Hamilton, Radosav S. Pantelic, Kelly H...
BMCBI
2007
265views more  BMCBI 2007»
15 years 6 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2007
113views more  BMCBI 2007»
15 years 6 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...