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» Building Large Knowledge Bases in Molecular Biology
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BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2011
14 years 9 months ago
To aggregate or not to aggregate high-dimensional classifiers
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
KDD
2009
ACM
189views Data Mining» more  KDD 2009»
16 years 25 days ago
CoCo: coding cost for parameter-free outlier detection
How can we automatically spot all outstanding observations in a data set? This question arises in a large variety of applications, e.g. in economy, biology and medicine. Existing ...
Christian Böhm, Katrin Haegler, Nikola S. M&u...
CIKM
2004
Springer
15 years 11 months ago
Hierarchical document categorization with support vector machines
Automatically categorizing documents into pre-defined topic hierarchies or taxonomies is a crucial step in knowledge and content management. Standard machine learning techniques ...
Lijuan Cai, Thomas Hofmann
BMCBI
2010
170views more  BMCBI 2010»
15 years 6 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...