Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
Background: Transcriptional regulation in eukaryotes often involves multiple transcription factors binding to the same transcription control region, and to understand the regulato...
Derek Y. Chiang, Alan M. Moses, Manolis Kamvysseli...
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Biological data, such as gene expression profiles or protein sequences, is often organized in a hierarchy of classes, where the instances assigned to "nearby" classes in...