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BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2007
124views more  BMCBI 2007»
15 years 6 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
BMCBI
2007
163views more  BMCBI 2007»
15 years 6 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
BMCBI
2010
88views more  BMCBI 2010»
15 years 6 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2008
98views more  BMCBI 2008»
15 years 6 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang