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BMCBI
2007
104views more  BMCBI 2007»
15 years 6 months ago
Comparative evaluation of gene-set analysis methods
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
BMCBI
2008
137views more  BMCBI 2008»
15 years 6 months ago
VennMaster: Area-proportional Euler diagrams for functional GO analysis of microarrays
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
Hans A. Kestler, André Müller, Johann ...
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems
Background: The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by ...
Nophar Geifman, Alon Monsonego, Eitan Rubin
BMCBI
2008
131views more  BMCBI 2008»
15 years 6 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...
BMCBI
2008
106views more  BMCBI 2008»
15 years 6 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
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