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BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
PURE: A webserver for the prediction of domains in unassigned regions in proteins
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
BMCBI
2008
155views more  BMCBI 2008»
15 years 6 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2007
146views more  BMCBI 2007»
15 years 6 months ago
Spatial location and its relevance for terminological inferences in bio-ontologies
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
Stefan Schulz, Kornél G. Markó, Udo ...
BMCBI
2007
143views more  BMCBI 2007»
15 years 6 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2007
135views more  BMCBI 2007»
15 years 6 months ago
UbiProt: a database of ubiquitylated proteins
Background: Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabol...
Alexander L. Chernorudskiy, Alejandro Garcia, Euge...
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