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VLDB
1999
ACM
224views Database» more  VLDB 1999»
15 years 11 months ago
Optimal Grid-Clustering: Towards Breaking the Curse of Dimensionality in High-Dimensional Clustering
Many applications require the clustering of large amounts of high-dimensional data. Most clustering algorithms, however, do not work e ectively and e ciently in highdimensional sp...
Alexander Hinneburg, Daniel A. Keim
BMCBI
2010
214views more  BMCBI 2010»
15 years 6 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
170views more  BMCBI 2010»
15 years 6 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2005
114views more  BMCBI 2005»
15 years 6 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
BMCBI
2011
15 years 1 months ago
Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions
Background: The amount of data on protein-protein interactions (PPIs) available in public databases and in the literature has rapidly expanded in recent years. PPI data can provid...
Nobuyoshi Sugaya, Toshio Furuya
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