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ISMB
1993
15 years 8 months ago
Protein Sequencing Experiment Planning Using Analogy
Experiment design and execution is a central activity in the natural sciences. The SeqERsystem provides a general architecture for the integration of automated planning techniques...
Brian P. Kettler, Lindley Darden
BIOINFORMATICS
2007
66views more  BIOINFORMATICS 2007»
15 years 6 months ago
Gene expression network analysis and applications to immunology
We address the problem of using expression data and prior biological knowledge to identify differentially expressed pathways or groups of genes. Following an idea of Ideker et al...
Serban Nacu, Rebecca Critchley-Thorne, Peter Lee, ...
BMCBI
2010
126views more  BMCBI 2010»
15 years 6 months ago
Simulation of a Petri net-based Model of the Terpenoid Biosynthesis Pathway
Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this ...
Aliah Hazmah Hawari, Zeti-Azura Mohamed-Hussein
BMCBI
2010
97views more  BMCBI 2010»
15 years 6 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou
ENTCS
2010
127views more  ENTCS 2010»
15 years 6 months ago
Combining Model Reductions
Molecular biological models usually suffer from a large combinatorial explosion. Indeed, proteins form complexes and modify each others, which leads to the formation of a huge num...
Ferdinanda Camporesi, Jérôme Feret, H...