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BMCBI
2005
212views more  BMCBI 2005»
15 years 6 months ago
PAGE: Parametric Analysis of Gene Set Enrichment
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Seon-Young Kim, David J. Volsky
BMCBI
2005
117views more  BMCBI 2005»
15 years 6 months ago
An evaluation of GO annotation retrieval for BioCreAtIvE and GOA
Background: The Gene Ontology Annotation (GOA) database http://www.ebi.ac.uk/GOA aims to provide high-quality supplementary GO annotation to proteins in the UniProt Knowledgebase....
Evelyn Camon, Daniel Barrell, Emily Dimmer, Vivian...
BMCBI
2004
162views more  BMCBI 2004»
15 years 6 months ago
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant m
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...
BIB
2010
140views more  BIB 2010»
15 years 4 months ago
Next generation sequencing in functional genomics
Genome-wide sequencing has enabled modern biomedical research to relate more and more events in healthy as well as disease-affected cells and tissues to the genomic sequence. Now ...
Thomas Werner
BIOINFORMATICS
2011
15 years 1 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj