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ASM
2010
ASM
16 years 1 months ago
An Imperative Extension to Alloy
We extend the Alloy language with the standard imperative constructs; we show the mix of declarative and imperative constructs to be useful in modeling dynamic systems. We present ...
Joseph P. Near, Daniel Jackson
CIBB
2008
15 years 8 months ago
Curating a Large-Scale Regulatory Network by Evaluating Its Consistency with Expression Datasets
Abstract. The analysis of large-scale regulatory models using data issued from genome-scale high-throughput experimental techniques is an actual challenge in the systems biology fi...
Carito Guziolowski, Jeremy Gruel, Ovidiu Radulescu...
ALIFE
2004
15 years 6 months ago
Basic Autonomy as a Fundamental Step in the Synthesis of Life
In the search for the primary roots of autonomy (a pivotal concept in Varela's comprehensive understanding of living beings), the theory of autopoiesis provided an explicit cr...
Kepa Ruiz-Mirazo, Alvaro Moreno
IDA
2009
Springer
15 years 4 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis
IDEAL
2003
Springer
15 years 12 months ago
Association Rule Mining Algorithms for Set-Valued Data
This paper presents an association rule mining system that is capable of handling set-valued attributes. Our previous research has exposed us to a variety of real-world biological ...
Christopher A. Shoemaker, Carolina Ruiz