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BMCBI
2008
121views more  BMCBI 2008»
15 years 6 months ago
Modularization of biochemical networks based on classification of Petri net t-invariants
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
EMO
2005
Springer
108views Optimization» more  EMO 2005»
16 years 4 days ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
ENTCS
2006
155views more  ENTCS 2006»
15 years 6 months ago
Biomolecular Agents as Multi-behavioural Concurrent Objects
In recent years, there has been increasing interest in computational models of biological systems based on various calculi of communicating processes, such as the stochastic pi-ca...
Denys Duchier, Céline Kuttler
AHS
2007
IEEE
226views Hardware» more  AHS 2007»
16 years 29 days ago
Application of Self-Configurability for Autonomous, Highly-Localized Self-Regulation
In this paper, key features of biological vs. artificial systems are identified, along with a synopsis of important consequences of those features. An artificial substrate that co...
Nicholas J. Macias, Peter M. Athanas
CMSB
2009
Springer
15 years 10 months ago
On Coupling Models Using Model-Checking: Effects of Irinotecan Injections on the Mammalian Cell Cycle
Abstract. In systems biology, the number of models of cellular processes increases rapidly, but re-using models in different contexts or for different questions remains a challengi...
Elisabetta De Maria, François Fages, Sylvai...