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CIKM
2010
Springer
15 years 5 months ago
Fast and accurate estimation of shortest paths in large graphs
Computing shortest paths between two given nodes is a fundamental operation over graphs, but known to be nontrivial over large disk-resident instances of graph data. While a numbe...
Andrey Gubichev, Srikanta J. Bedathur, Stephan Seu...
GECCO
2009
Springer
16 years 1 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
ALMOB
2006
155views more  ALMOB 2006»
15 years 6 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
CORR
2000
Springer
149views Education» more  CORR 2000»
15 years 6 months ago
On The Closest String and Substring Problems
Abstract. The problem of finding a center string that is "close" to every given string arises in computational molecular biology and coding theory. This problem has two v...
Ming Li, Bin Ma, Lusheng Wang
IPL
2007
96views more  IPL 2007»
15 years 6 months ago
On constructing an optimal consensus clustering from multiple clusterings
Computing a suitable measure of consensus among several clusterings on the same data is an important problem that arises in several areas such as computational biology and data mi...
Piotr Berman, Bhaskar DasGupta, Ming-Yang Kao, Jie...