Abstract. In order to guarantee that the optimal motif is found, traditional pattern-driven approaches perform an exhaustive search over all candidate motifs of length l. We develo...
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
We describe and demonstrate an algorithm that takes as input an unorganized set of points fx1; : : : ; xng IR3 on or near an unknown manifold M, and produces as output a simplicia...
Hugues Hoppe, Tony DeRose, Tom Duchamp, John Alan ...