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ISMB
2001
15 years 8 months ago
Designing fast converging phylogenetic methods
Abstract: Absolute fast converging phylogenetic reconstruction methods are provably guaranteed to recover the true tree with high probability from sequences that grow only polynomi...
Luay Nakhleh, Usman Roshan, Katherine St. John, Je...
ISMB
2001
15 years 8 months ago
Molecular classification of multiple tumor types
Using gene expression data to classify tumor types is a very promising tool in cancer diagnosis. Previous works show several pairs of tumor types can be successfully distinguished...
Chen-Hsiang Yeang, Sridhar Ramaswamy, Pablo Tamayo...
ISMB
1998
15 years 8 months ago
Modeling Protein Homopolymeric Repeats: Possible Polyglutamine Structural Motifs for Huntington's Disease
Wedescribe a prototype system (Poly-X) for assisting an expert user in modelingprotein repeats. Poly-X reduces the large numberof degrees of freedomrequired to specify a protein m...
Richard H. Lathrop, Malcolm S. Casale, Douglas J. ...
ISMB
1998
15 years 8 months ago
Bayesian Protein Family Classifier
A Bayesian procedure for the simultaneous alignment and classification of sequences into subclasses is described. This Gibbs sampling algorithm iterates between an alignment step ...
Kunbin Qu, Lee Ann McCue, Charles E. Lawrence
ISMB
1998
15 years 8 months ago
Automated Clustering and Assembly of Large EST Collections
The avMlability of large EST(Expressed Sequence Tag)databases has led to a revolution in the waynew genes are cloned. Difficulties arise, however,due to high error rates and redun...
David P. Yee, Darrell Conklin