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RECOMB
2008
Springer
16 years 7 months ago
Accounting for Non-genetic Factors Improves the Power of eQTL Studies
Abstract. The recent availability of large scale data sets profiling single nucleotide polymorphisms (SNPs) and gene expression across different human populations, has directed muc...
Oliver Stegle, Anitha Kannan, Richard Durbin, John...
RECOMB
2008
Springer
16 years 7 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
RECOMB
2008
Springer
16 years 7 months ago
Locating Multiple Gene Duplications through Reconciled Trees
We introduce the first exact and efficient algorithm for Guig?o et al.'s problem that, given a collection of rooted, binary gene trees and a rooted, binary species tree, deter...
J. Gordon Burleigh, Mukul S. Bansal, André ...
RECOMB
2008
Springer
16 years 7 months ago
CompostBin: A DNA Composition-Based Algorithm for Binning Environmental Shotgun Reads
A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional method...
Sourav Chatterji, Ichitaro Yamazaki, Zhaojun Bai, ...
RECOMB
2008
Springer
16 years 7 months ago
Rapid and Accurate Protein Side Chain Prediction with Local Backbone Information
High-accuracy protein structure modeling demands accurate and very fast side chain prediction since such a procedure must be repeatedly called at each step of structure refinement....
Jing Zhang, Xin Gao, Jinbo Xu, Ming Li