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RECOMB
2006
Springer
16 years 7 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
RECOMB
2005
Springer
16 years 7 months ago
Modeling the Combinatorial Functions of Multiple Transcription Factors
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...
Chen-Hsiang Yeang, Tommi Jaakkola
RECOMB
2003
Springer
16 years 7 months ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
RECOMB
2003
Springer
16 years 7 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
RECOMB
2002
Springer
16 years 7 months ago
Simulating a Coalescent Process with Recombination and Ascertainment
A new method is presented for use in simulating samples of disease and normal chromosomes bearing multiple linked genetic markers under a neutral model of mutation, genetic drift, ...
Ying Wang, Bruce Rannala