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BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
15 years 12 months ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
HPDC
2010
IEEE
15 years 7 months ago
Biocompute: towards a collaborative workspace for data intensive bio-science
The explosion of data in the biological community demands the development of more scalable and flexible portals for bioinformatic computation. To address this need, we put forth c...
Rory Carmichael, Patrick Braga-Henebry, Douglas Th...
BIOINFORMATICS
2010
116views more  BIOINFORMATICS 2010»
15 years 6 months ago
A principal skeleton algorithm for standardizing confocal images of fruit fly nervous systems
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
Lei Qu, Hanchuan Peng
BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
15 years 6 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 6 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...