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IMSCCS
2007
IEEE
16 years 27 days ago
Asymmetric Bagging and Feature Selection for Activities Prediction of Drug Molecules
Background: Activities of drug molecules can be predicted by QSAR (quantitative structure activity relationship) models, which overcomes the disadvantages of high cost and long cy...
Guo-Zheng Li, Hao-Hua Meng, Mary Qu Yang, Jack Y. ...
IMSCCS
2007
IEEE
16 years 27 days ago
Evolutionary Conservation of DNA-Contact residues in DNA-binding Domains
Background: DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DN...
Yao-Lin Chang, Huai-Kuang Tsai, Cheng-Yan Kao, Yun...
ISBRA
2007
Springer
16 years 22 days ago
Reconstruction of 3D Structures from Protein Contact Maps
Proteins are large organic compounds made of amino acids arranged in a linear chain (primary structure). Most proteins fold into unique threedimensional (3D) structures called inte...
Marco Vassura, Luciano Margara, Filippo Medri, Pie...
BIBE
2005
IEEE
121views Bioinformatics» more  BIBE 2005»
16 years 6 days ago
RNA Pseudoknot Prediction Using Term Rewriting
RNA plays a critical role in mediating every step of cellular information transfer from genes to functional proteins. Pseudoknots are widely occurring structural motifs found in a...
Xuezheng Fu, Hao Wang, William L. Harrison, Robert...
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
16 years 6 days ago
Highly Scalable and Accurate Seeds for Subsequence Alignment
We propose a method for finding seeds for the local alignment of two nucleotide sequences. Our method uses randomized algorithms to find approximate seeds. We present a dynamic ...
Abhijit Pol, Tamer Kahveci