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BIOINFORMATICS
2012
13 years 9 months ago
SSuMMo: rapid analysis, comparison and visualization of microbial communities
Motivation: Next-generation sequencing methods are generating increasingly massive datasets, yet still do not fully capture genetic diversity in the richest environments. To under...
Alex L. B. Leach, James P. J. Chong, Kelly R. Rede...
BIOINFORMATICS
2012
13 years 9 months ago
MolClass: a web portal to interrogate diverse small molecule screen datasets with different computational models
Summary: The MolClass toolkit and data portal generates computational models from user-defined small molecule datasets based on structural features identified in hit and non-hit m...
Jan Wildenhain, Nicholas FitzGerald, Mike Tyers
RECOMB
2010
Springer
16 years 1 months ago
Alignment-Free Phylogenetic Reconstruction
We introduce the first polynomial-time phylogenetic reconstruction algorithm under a model of sequence evolution allowing insertions and deletions—or indels. Given appropriate ...
Constantinos Daskalakis, Sébastien Roch
ASAP
2007
IEEE
122views Hardware» more  ASAP 2007»
16 years 29 days ago
Parallelizing HMMER for Hardware Acceleration on FPGAs
Profile based Hidden Markov Model is a widely used tool in bioinformatics. While being very valuable to biologists, it is extremely compute intensive and suffers from prohibitive...
Steven Derrien, Patrice Quinton
FUZZIEEE
2007
IEEE
16 years 28 days ago
On Using Fuzzy Contact Maps for Protein Structure Comparison
The comparison of protein structures is an important problem in Bioinformatics, and Soft Computing techniques were recently introduced for achieving a better representation and po...
Juan Ramón González, David A. Pelta