Motivation: Next-generation sequencing methods are generating increasingly massive datasets, yet still do not fully capture genetic diversity in the richest environments. To under...
Alex L. B. Leach, James P. J. Chong, Kelly R. Rede...
Summary: The MolClass toolkit and data portal generates computational models from user-defined small molecule datasets based on structural features identified in hit and non-hit m...
We introduce the first polynomial-time phylogenetic reconstruction algorithm under a model of sequence evolution allowing insertions and deletions—or indels. Given appropriate ...
Profile based Hidden Markov Model is a widely used tool in bioinformatics. While being very valuable to biologists, it is extremely compute intensive and suffers from prohibitive...
The comparison of protein structures is an important problem in Bioinformatics, and Soft Computing techniques were recently introduced for achieving a better representation and po...