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BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
15 years 8 months ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
BIBE
2005
IEEE
15 years 8 months ago
A Multi-Level Approach to SCOP Fold Recognition
The classification of proteins based on their structure can play an important role in the deduction or discovery of protein function. However, the relatively low number of solved...
Keith Marsolo, Srinivasan Parthasarathy, Chris H. ...
CSB
2005
IEEE
128views Bioinformatics» more  CSB 2005»
15 years 8 months ago
Application of a Generalized MWC Model for the Mathematical Simulation of Metabolic Pathways Regulated by Allosteric Enzymes
In our effort to elucidate the systems biology of the model organism, Escherichia coli, we have developed a mathematical model that simulates the allosteric regulation for threoni...
Tarek S. Najdi, Chin-Rang Yang, Bruce E. Shapiro, ...
CSB
2005
IEEE
165views Bioinformatics» more  CSB 2005»
15 years 8 months ago
Sequential Diagonal Linear Discriminant Analysis (SeqDLDA) for Microarray Classification and Gene Identification
In microarray classification we are faced with a very large number of features and very few training samples. This is a challenge for classical Linear Discriminant Analysis (LDA),...
Roger Pique-Regi, Antonio Ortega, Shahab Asgharzad...
DNA
2006
Springer
130views Bioinformatics» more  DNA 2006»
15 years 8 months ago
Displacement Whiplash PCR: Optimized Architecture and Experimental Validation
Whiplash PCR-based methods of biomolecular computation (BMC), while highly-versatile in principle, are well-known to suffer from a simple but serious form of self-poisoning known a...
John A. Rose, Ken Komiya, Satsuki Yaegashi, Masami...