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BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
16 years 8 days ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BIBE
2005
IEEE
16 years 8 days ago
Diagnostic Rules Induced by an Ensemble Method for Childhood Leukemia
We introduce a new ensemble method based on decision tree to discover significant and diversified rules for subtype classification of childhood acute lymphoblastic leukemia, a ...
Jinyan Li, Huiqing Liu, Ling Li
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
16 years 8 days ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...
BIBE
2005
IEEE
16 years 8 days ago
Improved Phylogenetic Motif Detection Using Parsimony
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
Usman Roshan, Dennis R. Livesay, David La
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
16 years 8 days ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...