The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
Ribonucleic acid (RNA) molecules contain the genetic information that regulates the functions of organisms. Given two different molecules, a preserved function corresponds to a pr...
While genomic sequencing projects have proved an abundant source of information for biological studies ranging from the molecular to the ecological in scale, much of the informati...
Douglas W. Raiford, Dan E. Krane, Travis E. Doom, ...
We show how chemical background knowledge can be used to improve the prediction performance in structureactivitity relationships (SARs) for non-congeneric compounds. The goal of t...
— Biological networks are formalized summaries of our knowledge about interactions among biological system components, like genes, proteins, or metabolites. From their global top...