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BIOCOMP
2010
15 years 4 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
BIOCOMP
2010
15 years 4 months ago
Robust Stability Analysis and Design Under Consideration of Multiple Feedback Loops in the Tryptophan Regulatory Network of E. c
The tryptophan operon of E. coli represents an important regulatory unit consisting of multiple feedback loops. The role of these loops is crucial to understand the dynamics of tr...
Anke Meyer-Bäse, Fabian J. Theis
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...
BMCBI
2010
155views more  BMCBI 2010»
15 years 6 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
BMCBI
2008
139views more  BMCBI 2008»
15 years 6 months ago
New challenges for text mining: mapping between text and manually curated pathways
Background: Associating literature with pathways poses new challenges to the Text Mining (TM) community. There are three main challenges to this task: (1) the identification of th...
Kanae Oda, Jin-Dong Kim, Tomoko Ohta, Daisuke Okan...