Clustering has been one of the most popular methods to discover useful biological insights from DNA microarray. An interesting paradigm is simultaneous clustering of both genes an...
The discovery of novel non-coding RNAs has been among the most exciting recent developments in Biology. Yet, many more remain undiscovered. It has been hypothesized that there is ...
Phylogenetic trees are commonly reconstructed based on hard optimization problems such as maximum parsimony (MP) and maximum likelihood (ML). Conventional MP heuristics for produc...
Usman Roshan, Bernard M. E. Moret, Tandy Warnow, T...
Effective analysis of genome sequences and associated functional data requires access to many different kinds of biological information. For example, when analysing gene expressio...
Mike Cornell, Norman W. Paton, Shengli Wu, Carole ...
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...