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BMCBI
2007
135views more  BMCBI 2007»
15 years 6 months ago
DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput
Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian ...
BMCBI
2008
77views more  BMCBI 2008»
15 years 6 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
BMCBI
2006
101views more  BMCBI 2006»
15 years 6 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
BIBE
2009
IEEE
126views Bioinformatics» more  BIBE 2009»
16 years 1 months ago
Mining Positional Association Super-Rules on Fixed-Size Protein Sequence Motifs
— Protein sequence motifs information is crucial to the analysis of biologically significant regions. The conserved regions have the potential to determine the role of the protei...
Bernard Chen, Sinan Kockara