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BIOCOMP
2010
15 years 3 months ago
A Network-based Approach to Classify Disease Stages of Prostate Cancer Using Quantitative Network Measures
Abstract-- This study deals with investigating the classification performance of information-theoretic measures when applied to complex biological networks. In particular, our aim ...
Laurin A. J. Mueller, Karl G. Kugler, Andreas Dand...
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
15 years 12 months ago
Open Microscopy Environment
High-throughput scoring of image-based biological assays heavily depends on the extraction of quantitative numerical information from microscopy images. This paper describes how t...
Ilya G. Goldberg
BIOINFORMATICS
2007
161views more  BIOINFORMATICS 2007»
15 years 6 months ago
Functional evaluation of domain-domain interactions and human protein interaction networks
: Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of...
Andreas Schlicker, Carola Huthmacher, Fidel Ram&ia...
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
15 years 6 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...