Background: Microarray-based measurement of mRNA abundance assumes a linear relationship between the fluorescence intensity and the dye concentration. In reality, however, the cal...
Leming M. Shi, Weida Tong, Zhenqiang Su, Tao Han, ...
Bioinformatics data is growing at a phenomenal rate. Besides the exponential growth of individual databases, the number of data depositories is increasing too. Because of the comp...
MoBIoS is a specialized database management system whose storage manager is based on metric-space indexing, and whose query language entails biological data types. When relational...
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Molecular-biological annotation data is continuously being collected, curated and made accessible in numerous public data sources. Integration of this data is a major challenge in ...