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» Bioinformatics and biological reality
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BMCBI
2006
180views more  BMCBI 2006»
15 years 6 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2008
106views more  BMCBI 2008»
15 years 6 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2006
109views more  BMCBI 2006»
15 years 6 months ago
iHOPerator: user-scripting a personalized bioinformatics Web, starting with the iHOP website
Background: User-scripts are programs stored in Web browsers that can manipulate the content of websites prior to display in the browser. They provide a novel mechanism by which u...
Benjamin M. Good, Edward A. Kawas, Byron Yu-Lin Ku...
BMCBI
2006
166views more  BMCBI 2006»
15 years 6 months ago
bioNMF: a versatile tool for non-negative matrix factorization in biology
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
SIGCSE
2002
ACM
118views Education» more  SIGCSE 2002»
15 years 5 months ago
A proposed undergraduate bioinformatics curriculum for computer scientists
Bioinformatics is a new and rapidly evolving discipline that has emerged from the fields of experimental molecular biology and biochemistry, and from the the artificial intelligen...
Travis E. Doom, Michael L. Raymer, Dan E. Krane, O...