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BMCBI
2008
156views more  BMCBI 2008»
15 years 6 months ago
The unique probe selector: a comprehensive web service for probe design and oligonucleotide arrays
Background: Nucleic acid hybridization, a fundamental technique in molecular biology, can be modified into very effective and sensitive methods for detecting particular targets mi...
Shu-Hwa Chen, Chen-Zen Lo, Ming-Chi Tsai, Chao A. ...
BMCBI
2006
174views more  BMCBI 2006»
15 years 6 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
GOPET: A tool for automated predictions of Gene Ontology terms
Background: Vast progress in sequencing projects has called for annotation on a large scale. A Number of methods have been developed to address this challenging task. These method...
Arunachalam Vinayagam, Coral del Val, Falk Schuber...
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
BMCBI
2006
78views more  BMCBI 2006»
15 years 6 months ago
An evaluation of human protein-protein interaction data in the public domain
Background: Protein-protein interaction (PPI) databases have become a major resource for investigating biological networks and pathways in cells. A number of publicly available re...
Suresh Mathivanan, Balamurugan Periaswamy, T. K. B...