Sciweavers

717 search results - page 119 / 144
» Bioinformatics and biological reality
Sort
View
BMCBI
2007
123views more  BMCBI 2007»
15 years 6 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BMCBI
2008
125views more  BMCBI 2008»
15 years 6 months ago
A fast algorithm for the multiple genome rearrangement problem with weighted reversals and transpositions
Background: Due to recent progress in genome sequencing, more and more data for phylogenetic reconstruction based on rearrangement distances between genomes become available. Howe...
Martin Bader, Mohamed Ibrahim Abouelhoda, Enno Ohl...
BMCBI
2007
105views more  BMCBI 2007»
15 years 6 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
BMCBI
2008
86views more  BMCBI 2008»
15 years 6 months ago
Piecewise multivariate modelling of sequential metabolic profiling data
Background: Modelling the time-related behaviour of biological systems is essential for understanding their dynamic responses to perturbations. In metabolic profiling studies, the...
Mattias Rantalainen, Olivier Cloarec, Timothy M. D...
BMCBI
2008
123views more  BMCBI 2008»
15 years 6 months ago
Functional module detection by functional flow pattern mining in protein interaction networks
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Young-Rae Cho, Lei Shi, Aidong Zhang