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» Bioinformatics and biological reality
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BMCBI
2008
100views more  BMCBI 2008»
15 years 6 months ago
Extracting unrecognized gene relationships from the biomedical literature via matrix factorizations
Background: The construction of literature-based networks of gene-gene interactions is one of the most important applications of text mining in bioinformatics. Extracting potentia...
Hyunsoo Kim, Haesun Park, Barry L. Drake
BMCBI
2008
74views more  BMCBI 2008»
15 years 6 months ago
Prediction of mucin-type O-glycosylation sites in mammalian proteins using the composition of k-spaced amino acid pairs
Background: As one of the most common protein post-translational modifications, glycosylation is involved in a variety of important biological processes. Computational identificat...
Yong-Zi Chen, Yu-Rong Tang, Zhi-Ya Sheng, Ziding Z...
BMCBI
2006
69views more  BMCBI 2006»
15 years 6 months ago
Retrieval with gene queries
Background: Accuracy of document retrieval from MEDLINE for gene queries is crucially important for many applications in bioinformatics. We explore five information retrieval-base...
Aditya Kumar Sehgal, Padmini Srinivasan
CPHYSICS
2007
84views more  CPHYSICS 2007»
15 years 6 months ago
Structural models of human big conductance calcium- and voltage-gated potassium channels
Human big conductance Ca2+ - and voltage-gated K+ channels (hBK) are putative drug targets for cardiovascular, respiratory and urological diseases. Here we have used molecular sim...
Agata Kranjc, Claudio Anselmi, Paolo Carloni, Fran...
NCA
2006
IEEE
15 years 6 months ago
Analysing the localisation sites of proteins through neural networks ensembles
Scientists involved in the area of proteomics are currently seeking integrated, customised and validated research solutions to better expedite their work in proteomics analyses and...
Aristoklis D. Anastasiadis, George D. Magoulas