Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Background. Software defect prediction has been one of the central topics of software engineering. Predicted defect counts have been used mainly to assess software quality and est...
Thomas Schulz, Lukasz Radlinski, Thomas Gorges, Wo...
Abstract--With the availability of powerful computational and communication systems, scientists now readily access large, complicated derived datasets and build on those results to...
Leon J. Osterweil, Lori A. Clarke, Aaron M. Elliso...
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...