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JMLR
2010
159views more  JMLR 2010»
15 years 1 months ago
Inference of Sparse Networks with Unobserved Variables. Application to Gene Regulatory Networks
Networks are becoming a unifying framework for modeling complex systems and network inference problems are frequently encountered in many fields. Here, I develop and apply a gener...
Nikolai Slavov
CMSB
2008
Springer
15 years 8 months ago
Automatic Complexity Analysis and Model Reduction of Nonlinear Biochemical Systems
Kinetic models for biochemical systems often comprise a large amount of coupled differential equations with species concentrations varying on different time scales. In this paper w...
Dirk Lebiedz, Dominik Skanda, Marc Fein
BMCBI
2007
132views more  BMCBI 2007»
15 years 6 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
EWCBR
2004
Springer
15 years 11 months ago
Maintaining Case-Based Reasoning Systems: A Machine Learning Approach
Over the years, many successful applications of case-based reasoning (CBR) systems have been developed in different areas. The performance of CBR systems depends on several factor...
Niloofar Arshadi, Igor Jurisica
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 11 months ago
Latent Structure Models for the Analysis of Gene Expression Data
Cluster methods have been successfully applied in gene expression data analysis to address tumor classification. By grouping tissue samples into homogeneous subsets, more systema...
Dong Hua, Dechang Chen, Xiuzhen Cheng, Abdou Youss...