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BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
ICDM
2008
IEEE
156views Data Mining» more  ICDM 2008»
16 years 23 days ago
Exploiting Local and Global Invariants for the Management of Large Scale Information Systems
This paper presents a data oriented approach to modeling the complex computing systems, in which an ensemble of correlation models are discovered to represent the system status. I...
Haifeng Chen, Haibin Cheng, Guofei Jiang, Kenji Yo...
BMCBI
2008
129views more  BMCBI 2008»
15 years 6 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2010
232views more  BMCBI 2010»
15 years 6 months ago
LucidDraw: Efficiently visualizing complex biochemical networks within MATLAB
Background: Biochemical networks play an essential role in systems biology. Rapidly growing network data and e research activities call for convenient visualization tools to aid i...
Sheng He, Juan Mei, Guiyang Shi, Zhengxiang Wang, ...
JOBIM
2000
15 years 10 months ago
InterDB, a Prediction-Oriented Protein Interaction Database for C. elegans
Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...
Nicolas Thierry-Mieg, Laurent Trilling